The settings that can be changed from the settings menu are:

Sound - On/Off
Turns the in-game sound effects on or off.

Bet Info - On/Off
When turned on, a window will be displayed next the cursor showing bet odds and payout.

Starting Cash
This setting defines how much money you will start a new game with.

New Game Tutorial - On/Off
When turned on, a beginners tutorial will be displayed whenever you start a new game.

Winnings Panel - On/Off
When turned on, the breakdown of the round winnings will be displayed after each roll of the dice (unless there was no losing or winning bets).
